|
Symbol Name ID |
Itgal
integrin alpha L MGI:96606 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Mouse Phenotypes | immune system phenotype |
abnormal leukocyte migration |
abnormal cellular extravasation |
abnormal diapedesis |
abnormal leukocyte tethering or rolling |
enhanced leukocyte tethering or rolling |
abnormal leukocyte adhesion |
decreased T cell proliferation |
enlarged spleen |
spleen hyperplasia |
increased eosinophil cell number |
decreased neutrophil cell number |
increased neutrophil cell number |
decreased B cell number |
decreased CD4-positive, alpha-beta T cell number |
increased CD4-positive, alpha-beta T cell number |
decreased CD8-positive, alpha-beta T cell number |
increased CD8-positive, alpha-beta T cell number |
decreased lymphocyte cell number |
increased monocyte cell number |
increased leukocyte cell number |
abnormal leukocyte physiology |
abnormal neutrophil physiology |
abnormal lymphocyte physiology |
impaired natural killer cell mediated cytotoxicity |
abnormal CD4-positive, alpha-beta T cell physiology |
abnormal cytotoxic T cell physiology |
decreased cytotoxic T cell cytolysis |
abnormal T cell activation |
increased circulating interleukin-10 level |
increased circulating interleukin-2 level |
increased circulating tumor necrosis factor level |
abnormal lymph node morphology |
lymph node hyperplasia |
small lymph nodes |
abnormal humoral immune response |
abnormal inflammatory response |
decreased susceptibility to endotoxin shock |
|
| Availability | Mouse Genotype | ||||||||||||||||||||||||||||||||||||||
| Itgaltm1.1Mshi/Itgaltm1.1Mshi | |||||||||||||||||||||||||||||||||||||||
| Itgaltm1Bll/Itgaltm1Bll | |||||||||||||||||||||||||||||||||||||||
| Itgaltm1Hlz/Itgaltm1Hlz | |||||||||||||||||||||||||||||||||||||||
| Itgaltm1Hogg/Itgaltm1Hogg | |||||||||||||||||||||||||||||||||||||||
| Itgaltm1Mak/Itgaltm1Mak | |||||||||||||||||||||||||||||||||||||||
| Itgaltm1Wpfl/Itgaltm1Wpfl | * | ||||||||||||||||||||||||||||||||||||||
| Itgaltm1Bll/Itgal+ | |||||||||||||||||||||||||||||||||||||||
| Itgaltm1Mak/Itgal+ | |||||||||||||||||||||||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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